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Estrogen Metabolism Chart

Good and Bad Estrogen

Estrogens are anabolic hormones, producing tissue growth. Since these hormones exert great biological activity in small doses, it is very important that the body effectively eliminates them. 

There are large variations in how women, and some men, metabolize estrogens. Some estrogens are considered to be "good" because they are associated with reduced cancer growth or having anticancer effects. "Bad" estrogens encourage tumor development and can cause DNA damage.


                       

The 2:16 Ratio

An important ratio is the 2:16 ratio (2-OHE and 16α-OHE1). Studies have shown this ratio provides an important indication of risk for future development of breast cancer. A low 2:16 ratio can indicate increased long-term risk for breast cancer as well as other estrogen-sensitive cancers including uterine, ovarian, cervical, prostate, and even head and neck cancers. However, this ratio is modifiable!

The Estronex Profile is both easy to use and cost-effective. With one simple urine collection, the test can determine levels of estrogens and how your body metabolizes them. Learn more…